REAGENT SYSTEM: Reagents transform into enchanted Potions via Catalysts (Aludel, Mortar & Pestle). The transformed Potion retains the Reagent's rarity and enchantment. Mak is the ONLY hero who can apply enchantments mid-run via alchemy. Philosopher's Stone, Calcinator, and Retort gain permanent buffs with every reagent transformed.
Playstyle
Survives early via regeneration, then transitions to scaling damage. Commit to one damage type (poison, burn, or weapon). The Poppy Field + Spider Mace + Floor Spike combo is considered potentially the strongest build in the entire game.
Top Builds — Season 14
Expert Tips
Obsidian enchantment doubles damage — transforms slow poison items into powerhouses.
Poppy Field + Spider Mace + Floor Spike is potentially the best combo in the game.
Retort, Philosopher's Stone, and Calcinator stack PERMANENTLY each run — transform reagents constantly.
Mak has 'Mak-levels of regen' — you can survive early losses that would kill other heroes.
Key Items
Deals damage and applies significant Poison. Considered potentially the best build anchor in the entire game.
The S-tier Mak combo: Poppy Field + Spider Mace + Floor Spike. Together they create a Poison machine with absurd late-game ceiling.
Applies Poison on activation. Pairs with Floor Spike and Poppy Field for stacking Poison.
Part of the Poppy Field trinity. Each of these three items applies Poison, creating rapidly stacking Poison damage.
Small item that applies Poison. Slot-efficient Poison stacker.
The small slot in the Poppy Field trinity. Applies Poison from a 1-slot item, freeing space for other synergies.
Gains +1-4 Regen permanently each time you transform a Reagent during the run. Provides base Regen that scales all run.
Transform reagents from Day 1 onward. By mid-run, Philosopher's Stone provides massive passive Regen, making Mak nearly unkillable.
Gains +4-7 Poison permanently each time you transform a Reagent. Stacks all run.
Transform reagents constantly — Retort's Poison value grows every time. By Day 10, Retort's passive Poison alone can be lethal.
Deals 200 damage and applies Regen. Scales damage based on HP thresholds crossed during the fight.
Damage scales as your HP drops — rewards staying alive but not at full health. Pairs with self-poison for controlled HP manipulation.
Economy item that generates gold and provides buffs. The backbone of Mak's A+ Peacewrought build.
Supports Library-style play — use gold to buy more reagents, transform more reagents, permanently stack Philosopher's Stone/Retort/Calcinator.
Applies Slow to 1/2/3 items for 3 seconds. Also functions as a Reagent.
Dual use: Slow control + Reagent for transformation. Toxic enchantment doubles its Poison value when transformed.
Poison-scaling weapon with Multicast. Gains additional Poison with each activation.
Stacks its own Poison permanently during a fight. Combined with Retort's passive Poison, late-game Plague Glaive hits are devastating.
Gains +4-7 Burn permanently each time you transform a Reagent. Stacks all run.
Transform reagents from Day 1 to maximize Calcinator's burn stacks. By late-game, passive Calcinator burn is a secondary win condition.
Scales damage on critical hits. Each crit increases its permanent damage.
Pair with Deadly enchantment (50% crit chance) on adjacent items. Each crit permanently increases Magic Carpet's damage — snowball item.
Self-poisons your player while also granting Regen and Lifesteal. The Regen counters the self-poison.
Core of Mak's Self-Poison build. The self-applied Poison is countered by the Regen — net result is free Lifesteal and poison synergy items proc constantly.
Enhances all Potions in your board. Note: as of Season 14, no longer generates potions from other heroes' items.
Stack potions and let Distillery make all of them hit harder. Build around high-quality Potions for maximum value.